Protease Inhibitors and Phosphatase Inhibitors
Cayman Chemical GlutamInase InhIbItr comp 1mg
A cell-permeable, reversible inhibitor of a mitochondrial glutaminase splice variant, glutaminase C (IC50 = ~2.5 µM), which is commonly found in cancer cells; blocks transformation induced by Rho GTPases and inhibits the proliferation of cancer cell lines without affecting normal cells
Selleck Chemical LLC Epirubicin HCl 25mg 56390-09-1 4'-epidoxorubicin HCl
Epirubicin HCl (4'-epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin induces apoptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
CPC Scientific DNP-Pro-Leu-Gly-Cys(Me)-His-Ala-DArg-NH2 (trifluoroacetate salt) 1MG
Efficient substrate for interstitial/vertebrate collagenase (MMP-1), stromelysin (MMP-3), gelatinases (MMP-2 and MMP-9) and punctuated metalloproteinase (MMP-7). ONE-LETTER SEQUENCE: Dnp-PLG-Cys(Me)-HA-DArg-NH2MOLECULAR FORMULA: C38H57N15O11S1MOLECULAR WEIGHT:932.03STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [145224-98-2], SYNONYMS: Dnp-Pro-Leu-Gly-Cys(Me)-His-Ala-D-Arg-NHRESEARCH AREA: CancerREFERENCES: J. Berman et al, JBC, 267, 1434 (1992)
Cayman Chemical USP7-USP47 InhIbItr 5mg
A dual inhibitor of USP7 and USP47 (IC50s = 0.42 and 1 μM, respectively); selective for USP7 and USP47 over USP2, USP5, USP8, USP21, USP28, caspase-3, and cathepsin B (IC50s = >31.6 μM); inhibits the growth of HCT116 cells (EC50 = 7.6 μM)
Enzo Life Sciences PKSI-527 (5mg). CAS: 128837-71-8
Highly selective plasma kallikrein inhibitor (Ki = 0.81 µM). Can be used for affinity purification of kalikrein. Suppresses collagen-induced arthritis in a mouse model. Synergizes with NO donors producing antithrombotic effects ex vivo. Alternative name: trans-4-Aminomethylcyclohexanecarbonyl-phenylalanyl-4-carboxymethylanilide. Purity: ≥95% (HPLC). Solubility: Soluble in water (5 mg/ml). Long Term Storage: -20°C.
Cayman Chemical h-e5NT InhIbItr 5C 1mg
An inhibitor of ecto-5'-nucleotidase (IC50s = 0.37 and 1.66 µM for the human and rat enzymes, respectively); inhibits ENPP1, ENPP3, and TNAP (IC50s = 1.12, 1.37, and 1.48 µM, respectively, for the human enzymes)
Indofine Chemical Leupeptin Hemisulp, 90%, 25 Mg
LEUPEPTIN HEMISULPHATE 25 MG, Products for Life Science, Ac-Leu-Leu-argininal hemisulphate, 2 C20H38N6O4 . H2O4S, MW: 951.19, >90%, 103476-89-7, MFCD00037012
CPC Scientific FITC-C6-Pro-Leu-Ala-Leu-Trp-Ala-Arg-Lys(Biotin)-NH2 (trifluoroacetate salt) 0.5MG
ONE-LETTER SEQUENCE: FITC-C6-PLALWAR-Lys(Biotin)-NH2MOLECULAR FORMULA: C83H112N18O16S2MOLECULAR WEIGHT:1682.02STORAGE CONDITIONS: -20 5CRESEARCH AREA: CancerREFERENCES: E.J. Jacobsen, et al., J. Med. Chem. 42, 1525 (1999); J.V. Manetta, et al., Anal. Biochem. 202, 10 (1992)
Medchemexpress LLC PM-81I | 1637532-83-2 | 99.9% | 845.91 | 1 MG
PM-81I is a potent STAT6 inhibitor that targets the SH2 structural domain, effectively reducing STAT6 phosphorylation levels. This compound is valuable for studies in areas such as allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease, and cancer. It is supplied as a white to off-white solid with high purity.
- Potent STAT6 inhibitor
- Targets SH2 structural domain
- Reduces STAT6 phosphorylation levels
- Useful for allergic lung disease research
- Useful for allergic rhinitis research
- Useful for chronic obstructive pulmonary disease research
- Useful for cancer research
- White to off-white solid appearance
- High purity
Echelon Biosciences Research Labs BODIPY TMR-PI(5)P 100 ug
BODIPY TMR PI(5)P (BODIPY TMR Phosphatidylinositol 5-phosphate) is a water soluble analog of PI(5)P labeled with the orange fluorophore, Bodipy-TMR, at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable
Selleck Chemical LLC AC480 (BMS-599626) 5mg 714971-09-2
AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.